Immunotherapy With a Ragweed-Toll-Like Receptor 9 Agonist Vaccine for Allergic Rhinitis
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چکیده
منابع مشابه
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.
BACKGROUND Conjugating immunostimulatory sequences of DNA to specific allergens offers a new approach to allergen immunotherapy that reduces acute allergic responses. METHODS We conducted a randomized, double-blind, placebo-controlled phase 2 trial of a vaccine consisting of Amb a 1, a ragweed-pollen antigen, conjugated to a phosphorothioate oligodeoxyribonucleotide immunostimulatory sequence...
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ژورنال
عنوان ژورنال: Pediatrics
سال: 2007
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2007-0846gggg